Eosinophilic Infiltration in the Liver: Unusual Manifestation of Hepatic Segmental Involvement

Histopathologically, eosinophilic infiltration in the liver (or focal eosinophilic liver disease) includes eosinophilic infiltration in the periportal space, eosinophilic abscess, and eosinophilic granuloma. Eosinophilic infiltration in the liver is related common and is often associated with various eosinophil-related conditions. It is almost correlated with eosinophilia (defined as 500 eosinophils/ l in the peripheral blood) and incidentally discovered on radiologic examinations, such as ultrasonography or computed tomography, and is usually demonstrated as multiple, small, poorly defined, round or oval nodular lesions (1-4). However, in patients with a history of malignancy, it sometimes may mimic hepatic metastases and unnecessary biopsy or surgery were performed. In this case, we described that eosinophilic infiltration in the liver presented as an unusual segmental involvement. A 68-year-old Asian female who had undergone mastectomy due to breast cancer 9 years prior to presentation at our clinic complained of fever and CASE REPORT INTRODUCTION www.ksmrm.org JKSMRM 16(1) : 76-80, 2012